Action of endogenous neuraminidase on sialo compounds in the developing chick retina.

myelin was observed to be much more extensively labelled than the intact tissue samples. Quantification of the results has now to be carried out, but these initial studies suggest that the approach is feasible for investigating the localization of cerebroside in the myelin sheath of central-nerve tissue. Re-swelling of the central-nerve tissue is essential in this approach, for it enables galactose oxidase to penetrate into the separated myelin lamellae and to act on galactose cerebroside residues which are exposed.